Author:
Rochman Susan,Mills Dixie,Kim Julian,Kuerer Henry,Love Susan
Abstract
Abstract
Researchers are using the intraductal approach to advance breast cancer risk assessment, prevention, diagnosis, and treatment. Procedures and technologies that can access and interrogate the ductal-alveolar systems include nipple aspiration, ductal lavage and ductoscopy. Ductoscopic papillectomy, ductoscopic margin evaluation, and intraductal therapy are considered promising investigational and innovative treatments. These techniques are used to explore the biology of the normal breast; collect and analyze breast fluid and cells to identify biomarkers that can be used in breast cancer detection and risk assessment; and to identify new ways to find and administer therapeutic and/or preventive agents to the breast tissue. This report summarizes the latest research findings in these areas, presented at The 6th International Symposium on the Intraductal Approach to Breast Cancer in 2009.
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference24 articles.
1. Papanicolaou GN, Holmquist DG, Bader GM, Falk EA: Exfoliative cytology of the human mammary gland and its value in the diagnosis of cancer and other diseases of the breast. Cancer. 1958, 11: 377-409. 10.1002/1097-0142(195803/04)11:2<377::AID-CNCR2820110223>3.0.CO;2-A.
2. Petrakis NL, Mason L, Lee R, Sugimoto B, Pawson S, Catchpool F: Association of race, age, menopausal status, and cerumen type with breast fluid secretion in nonlactating women, as determined by nipple aspiration. J Natl Cancer Inst. 1975, 54: 829-834.
3. Sartorius OW, Smith HS, Morris P, Benedict D, Friesen L: Cytologic evaluation of breast fluid in the detection of breast disease. J Natl Cancer Inst. 1977, 59: 1073-1080.
4. Rose DP, Lahti H, Laakso K, Kettunen K, Wynder EL: Serum and breast duct fluid prolactin and estrogen levels in healthy Finnish and American women and patients with fibrocystic disease. Cancer. 1986, 57: 1550-1554. 10.1002/1097-0142(19860415)57:8<1550::AID-CNCR2820570819>3.0.CO;2-C.
5. Wrensch MR, Petrakis NL, King EB, Miike R, Mason L, Chew KL, Lee MM, Ernster VL, Hilton JF, Schweitzer R, et al: Breast cancer incidence in women with abnormal cytology in nipple aspirates of breast fluid. Am J Epidemiol. 1992, 135: 130-141.
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