Abstract
Abstract
Background
Bronchial thermoplasty (BT) is a novel bronchoscopic intervention for severe persistent asthma. An increase in transient respiratory adverse events associated with BT were noted over the treatment periods, however, these events appear sporadic and should not always recur in a single individual and BT-related pneumonia has rarely been reported.
Case presentation
We present a case of uncontrolled severe asthma who developed puzzling pneumonia sequentially after each session of BT procedures. After each operation of three sequential BT procedures, she developed cough and purulent expectoration when her chest radiology showed new infiltrates right in the treatment regions. After empirical use of antibacterial agents plus physiotherapy and postural sputum drainage, her symptoms vanished and chest imaging resumed normal.
Conclusion
The originality of our case report is related to the recurrence of pneumonia after three sequential BT procedures. To date, similar report has not been available in the literature. We hope to prompt alerts for post-BT respiratory infections, although most of them, along with other adverse events, are mild and tractable.
Funder
Capital Key Science Program for Health Development
Publisher
Springer Science and Business Media LLC
Subject
Pulmonary and Respiratory Medicine
Reference17 articles.
1. Cox G, Miller JD, McWilliams A, et al. Bronchial thermoplasty for asthma. Am J Respir Crit Care Med. 2006;173:965–9 [PubMed: 16456145].
2. Pavord ID, Cox G, Thomson NC, et al. Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med. 2007;176:1185–91 [PubMed: 17901415].
3. Castro M, Rubin AS, Laviolette M, et al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med. 2010;181:116–24 [PubMed: 19815809].
4. Castro M, Rubin A, Laviolette M, et al. Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma. Ann Allergy Asthma Immunol. 2011;107:65–70 [PubMed: 21704887].
5. Nong Y, Su N, Lin J, et al. Effectiveness and safety of bronchial thermoplasty in patients with severe asthma. Zhonghua Jie He He Hu Xi Za Zhi. 2016;39:177–82 [PubMed: 26980530].
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Prednisone;Reactions Weekly;2020-10