Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons-Reference-Cited by-同舟云学术

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Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons

Published:2018-03-22 Issue:1 Volume:9 Page:
ISSN:2040-2392
Container-title:Molecular Autism
language:en
Short-container-title:Molecular Autism

Author:

Jung Matthias,Häberle Benjamin M.,Tschaikowsky Tristan,Wittmann Marie-Theres,Balta Elli-Anna,Stadler Vivien-Charlott,Zweier Christiane,Dörfler Arnd,Gloeckner Christian Johannes,Lie D. Chichung

Funder

Deutsche Forschungsgemeinschaft

Interdisziplinäres Zentrum für Klinische Forschung Erlangen

Helmholtz-Gemeinschaft

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health,Developmental Biology,Developmental Neuroscience,Molecular Biology

Link

http://link.springer.com/content/pdf/10.1186/s13229-018-0200-1.pdf

Reference46 articles.

1. Massari ME, Murre C. Helix-Loop-Helix proteins: regulators of transcription in eucaryotic organisms. Mol Cell Biol. 2000;20:429–40.

2. Amiel J, Rio M, de Pontual L, Redon R, Malan V, Boddaert N, Plouin P, Carter NP, Lyonnet S, Munnich A, Colleaux L. Mutations in TCF4, encoding a class I basic helix-loop-helix transcription factor, are responsible for Pitt-Hopkins syndrome, a severe epileptic encephalopathy associated with autonomic dysfunction. Am J Hum Genet. 2007;80:988–93.

3. Zweier C, Peippo MM, Hoyer J, Sousa S, Bottani A, Clayton-Smith J, Reardon W, Saraiva J, Cabral A, Gohring I, et al. Haploinsufficiency of TCF4 causes syndromal mental retardation with intermittent hyperventilation (Pitt-Hopkins syndrome). Am J Hum Genet. 2007;80:994–1001.

4. Schizophrenia Psychiatric Genome-Wide Association Study C. Genome-wide association study identifies five new schizophrenia loci. Nat Genet. 2011;43:969–76.

5. Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietilainen OP, Mors O, Mortensen PB, et al. Common variants conferring risk of schizophrenia. Nature. 2009;460:744–7.

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