The Brazilian Society of Rheumatology guidelines for axial spondyloarthritis – 2019

Author:

Resende Gustavo GomesORCID,Meirelles Eduardo de Souza,Marques Cláudia Diniz Lopes,Chiereghin Adriano,Lyrio Andre Marun,Ximenes Antônio Carlos,Saad Carla Gonçalves,Gonçalves Célio Roberto,Kohem Charles Lubianca,Schainberg Cláudia Goldenstein,Campanholo Cristiano Barbosa,Bueno Filho Júlio Silvio de Sousa,Pieruccetti Lenise Brandao,Keiserman Mauro Waldemar,Yazbek Michel Alexandre,Palominos Penelope Esther,Goncalves Rafaela Silva Guimarães,Lage Ricardo da Cruz,Assad Rodrigo Luppino,Bonfiglioli Rubens,Anti Sônia Maria Alvarenga,Carneiro Sueli,Oliveira Thauana Luíza,Azevedo Valderílio Feijó,Bianchi Washington Alves,Bernardo Wanderley Marques,Pinheiro Marcelo de Medeiros,Sampaio-Barros Percival Degrava

Abstract

AbstractSpondyloarthritis is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. The classification axial spondyloarthritis is adopted when the spine and/or the sacroiliac joints are predominantly involved. This version of recommendations replaces the previous guidelines published in May 2013.A systematic literature review was performed, and two hundred thirty-seven studies were selected and used to formulate 29 recommendations answering 15 clinical questions, which were divided into four sections: diagnosis, non-pharmacological therapy, conventional drug therapy and biological therapy. For each recommendation the level of evidence supporting (highest available), the strength grade according to Oxford, and the degree of expert agreement (inter-rater reliability) is informed.These guidelines bring evidence-based information on clinical management of axial SpA patients, including, diagnosis, treatment, and prognosis.

Funder

Sociedade Brasileira de Reumatologia

Publisher

Springer Science and Business Media LLC

Subject

Rheumatology

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