Ovotesticular disorder of sex development in a 46 XY adolescent: a rare case report with review of the literature

Author:

Bbs Koui,Ad Abouna,Djiwa Toukilnan,B Traore,M Kouyate,Ke Kouame,Na Aman

Abstract

Abstract Introduction : Ovotestis is a rare cause of sexual ambiguity characterized by the presence in a patient of both testicular and ovarian tissue, leading to the development of both male and female structures. We report a case of ovotestis diagnosed in an adolescent, with a review of the literature. Case Report A 15-year-old patient presented with a right scrotal swelling associated with gynecomastia. Histology showed a juxtaposition of ovarian stroma with ovarian follicle and seminiferous tubules. Karyotype revealed a male subject (XY). We have therefore retained the diagnosis of ovotesticular disorders of sex development. Conclusion Ovotestis is a rare finding, heterogeneous in its genetic etiology and clinical presentation. While many patients are diagnosed during infancy or childhood, we presented a case diagnosed in a 15-year-old adolescent.

Publisher

Springer Science and Business Media LLC

Subject

Obstetrics and Gynecology,Reproductive Medicine,General Medicine

Reference20 articles.

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3. Ozsu E, Mutlu GY, Cizmecioglu FM, Ekingen G, Muezzinoglu B, Hatun S. Ovotesticular disorder of sexual development and a rare 46,XX/47,XXY karyotype. J Pediatr Endocrinol Metab JPEM. 2013;26:789–91.

4. Matsui F, Shimada K, Matsumoto F, Itesako T, Nara K, Ida S, et al. Long-term outcome of ovotesticular disorder of sex development: a single center experience. Int J Urol off J Jpn Urol Assoc. 2011;18:231–6.

5. Meftah A, Moumen A, Eljadi H, Gaouzi A. Ovotestis 46 xy: a propos d’un cas. Ann Endocrinol. 2016;77(4):481.

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