Author:
Odeja Oluwakayode,Obi Grace,Ogwuche Christiana Ene,Elemike Elias Emeka,Oderinlo Yemi
Abstract
Abstract
Background
Phytochemical screening, antimicrobial and antioxidant activities of
the hexane, ethylacetate and methanol crude extracts of Senna occidentalis (L.) leaves were studied in this work. The
aim of the work is to ascertain the level of antimicrobial and antioxidant
properties of different solvent extracts of Senna
occidentalis plant.
Methods
The preliminary screening of the various extracts was carried out
using standard methods and the results revealed the presence of tannins,
alkaloids, reducing sugar, phenols, anthraquinones, resins, saponins and
glycosides. The antimicrobial screening was carried out using the following
organisms; Staphylococcus aureus, Eshericha coli,
Bacillus subtilis, Pseudomonas aeruguinosa, Salmonella typhi, Klebsiellae
pneumoniae, Candida albicans, Aspergillus niger, Penicillium
notatum and Rhizopus
stolonifer. The free radical scavenging capacity using hydrogen
peroxide was equally determined to evaluate the antioxidant activities of the
extracts.
Results
The results obtained showed that Senna
occidentalis (L.) leaf extracts have interesting pharmacological
active compounds with great radical scavenging and antimicrobial effects and as
such could be used in ethno medicine for treatment of some infections and
ailments.
Conclusion
Further investigations on the chemical compositions and possible isolation of
active ingredients would be carried out.
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
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