Bedside testing of CYP2C19 gene for treatment of patients with PCI with antiplatelet therapy
Author:
Funder
King Abdulaziz City for Science and Technology
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1186/s12872-020-01558-2.pdf
Reference24 articles.
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2. Collet JP, Hulot JS, Pena A, Villard E, Esteve JB, Silvain J, et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet. 2009;373(9660):309–17. https://doi.org/10.1016/S0140-6736(08)61845-0 Epub 2008 Dec 26.
3. Cutlip DE, Windecker S, Mehran R, Boam A, Cohen DJ, van Es GA, et al. Clinical end points in coronary stent trials: a case for standardized definitions. Circulation. 2007;115(17):2344–51. https://doi.org/10.1161/CIRCULATIONAHA.106.685313 .
4. Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, et al. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos. 2010;38(1):92–9. https://doi.org/10.1124/dmd.109.029132 .
5. Al-Jenoobi FI, Alkharfy KM, Alghamdi AM, Bagulb KM, Al-Mohizea AM, Al-Muhsen S, et al. CYP2C19 genetic polymorphism in Saudi Arabians. Basic Clin Pharmacol Toxicol. 2013;112(1):50–4. https://doi.org/10.1111/j.1742-7843.2012.00919.x .
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