Abstract
Abstract
Background
Patients with both double orifice mitral valve (DOMV) and bicuspid aortic valve (BAV) malformation are rare. Although DOMV or BAV can be detected in some genetic syndromes, it has not been reported to simultaneously appear in Turner syndrome (TS). TrueVue, TouchVue, and TrueVue Glass are the latest technologies in advanced three-dimensional echocardiography (3DE), which is an important information supplement to two-dimensional echocardiography (2DE) for the diagnosis of congenital cardiac malformations. Herein we report the novel use of the above-mentioned technologies in the diagnosis and evaluation of a rare, combined valve malformation. Meanwhile, we also reviewed the literature for cases involving both DOMV and BAV and their association with various genetic syndromes.
Case presentation
We present the case of a 5-year-old girl diagnosed with TS because of a developmental delay. DOMV and BAV were found through echocardiographic examination. Three-dimensional transthoracic echocardiography as well as a series of novel advanced techniques were applied to clearly display the spatial structure of all tiers of the mitral valve apparatus, aortic valve, and arch to facilitate an accurate diagnosis.
Conclusions
This is the first case in which both DOMV and BAV were associated with TS. Innovative TrueVue and TrueVue Glass offer unprecedented photographic stereoscopic images, while TouchVue technology greatly improved the ultrasonic diagnostic workflow and the diagnostic performance of rare valve malformations by adding virtual light sources to display realistic light-shadow effects.
Funder
Young Scientists Fund of the National Natural Science Foundation of China
Liaoning Provincial Natural Science Key Project of China
345 Talent Project
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Reference37 articles.
1. Das BB, Pauliks LB, Knudson OA, Kirby S, Chan KC, Valdes-Cruz L, Cayre RO. Double-orifice mitral valve with intact atrioventricular septum: an echocardiographic study with anatomic and functional considerations. J Am Soc Echocardiogr. 2005;18(3):231–6.
2. Barbero U, Ho SY. Anatomy of the atria: a road map to the left atrial appendage. Herzschrittmacherther Elektrophysiol. 2017;28(4):347–54.
3. Benjamin MM, Banga S, Sengupta PP, Mills JD, Hamirani YS. Double-orifice mitral valve associated with bicuspid aortic valve and primary pulmonary vein stenosis. CASE (Philadelphia, Pa). 2020;4(3):152–4.
4. Liu S, Ren W, Ma C, Yang J. Congenital double-orifice mitral valve in asymptomatic patients comprehensive assessment by three-dimensional echocardiography. Int Heart J. 2018;59(1):213–5.
5. Balistreri CR, Forte M, Greco E, Paneni F, Cavarretta E, Frati G, Sciarretta S. An overview of the molecular mechanisms underlying development and progression of bicuspid aortic valve disease. J Mol Cell Cardiol. 2019;132:146–53.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献