Author:
Abbas Hanine,Hallit Souheil,Kurdi Mazen,Karam Rita
Abstract
Abstract
Background
Drug non-adherence is assumed to play an important role in development of hypertensive urgency, which is a common health problem resulting in frequent emergency department admissions and thus increased healthcare spending wastage. The objective of this study is to assess the rate of non-adherence to antihypertensives and to evaluate influencing factors predicting this behavior in Lebanese hypertensive adults. In addition, this study aim to estimate the cost of hospitalization for hypertensive urgency covered by the Ministry of Public Health in patients’ non-adherent to their antihypertensives.
Methods
A multi-methods approach is used comprising a cross-sectional study, additionally to an observational, retrospective, cost of illness study. A cross-sectional questionnaire based study is conducted from May to Dec, 2019 to address the study objective. Using the Ministry of Public Health hospitalization data during 2019, the cost of hospitalization for hypertensive urgency is assessed. Multivariable analysis is performed to calculate the adjusted odd ratios by fitting a logistic regression model.
Results
The cross-sectional study includes 494 participants and shows that 43.0% of patients hospitalized and covered by the Ministry of Public Health are non-adherent. The univariate regression model shows that adherence to antihypertensive medications is significantly associated with age (p-value = 0.005) and follow-up visits (p-value = 0.046). The odds of adherence for participants earning more than USD 2000 was 3.27 times that for those who earn less than USD 1000 (p = 0.026). The estimated cost of hospitalization for non-adherent patients is USD 452,353 in 2019.
Conclusion
Non-adherence associated hospitalization costs represents a financial burden to Lebanese health system.
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Reference25 articles.
1. Owens P, Mutter R. Statistical brief #100 emergency department visits for adults in community hospitals. Agency for Healthcare Research and Quality. (Accessed March 19, 2020]. http://www.hcup-us.ahrq.gov/reports/statbriefs/sb100.pdf. Cutler RL, Fernandez-Llimos F, Frommer M, Benrimoj C, Garcia-Cardenas V. Economic impact of medication non-adherence by disease groups: a systematic review. BMJ Open 2018; 8:e016982. Doi: https://doi.org/10.1136/bmjopen-2017-016982.
2. Aitken M, Valkova S. Avoidable costs in US healthcare: the $200 billion opportunity from using medicines more responsibly. United States: IMS Institute for Healthcare Informatics; 2013. p. 20–1.
3. Lloyd J, Maresh S, Christopher A, et al. How much does medication non-adherence cost the Medicare fee-for-service program? Med Care. 2019;3(57):218–24. https://doi.org/10.1097/MLR.0000000000001067.
4. Australian Institute of Health and Welfare. Health expenditure Australia 2015–16. Health and welfare expenditure series. Cat. no. HWE 68. Vol. 58. Canberra: AIHW; 2017.
5. Pajaree M, Darren MA, Norman S, Chuenjid K. Hospital admissions associated with medication non-adherence: a systematic review of prospective observational studies. BMJ. 2018;27:11. https://doi.org/10.1136/bmjqs-2017-007453.
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