Author:
Langie Renan,Pacheco Viviane Neves,Szydloski Vinicius Matheus,Corsetti Adriana,de Quevedo Alexandre Silva,da Silva Fábio Pinto,Collares Fabrício Mezzomo,Visioli Fernanda,Ponzoni Deise,Puricelli Edela
Abstract
Abstract
Background
The aim of this study was to establish a sheep model of the Puricelli biconvex arthroplasty (ABiP) technique in sheep for evaluating its functional, biological and histological parameters.
Methods
Ten Corriedale black sheep were submitted to TMJ total reconstruction with poly(methyl methacrylate) (PMMA) using ABiP and euthanized after 45 (n = 5) or 90 (n = 5) days. Control animals (n = 2) underwent sham operations and were euthanized after 45 days. Variables were assessed before the surgery (T0), immediately after (T1) and at 45 or 90 postoperative days (T2).
Results
Histological analyses showed regression of inflammatory cells over the follow-up period. PMMA showed reduced porosity and roughness in the articular contact area. PMMA temporal components showed linear and volumetric wear in comparison to control, but no foreign body reaction was observed. The reconstructions were stable in all animals. The amplitude of mouth opening and left lateral movements were maintained, except for a reduction in the range of right lateral movements at day 90 in the experimental group. Clinical, macroscopic and radiographic observations showed that the reconstructions were stable.
Conclusions
The analysis of functional, biological and histological parameters in sheep submitted to ABiP showed stable results of the procedure, with maintenance of body weight and all mandibular movements, save contralateral mandibular movement, suggesting that joint function was completely maintained following the procedure. This experimental study provides support for clinical results previously reported of the ABiP technique in TMJ reconstruction procedures.
Funder
Clinics Hospital of Porto Alegre – University Hospital, Federal University of Rio Grande do Sul (UFRGS), Brazil
Publisher
Springer Science and Business Media LLC
Subject
Neurology (clinical),General Dentistry,Otorhinolaryngology