A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance-Reference-Cited by-同舟云学术

A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance

Published:2017-10-11 Issue:1 Volume:18 Page:
ISSN:1471-2164
Container-title:BMC Genomics
language:en
Short-container-title:BMC Genomics

Author:

Sheen Patricia,Requena David,Gushiken Eduardo,Gilman Robert H.,Antiparra Ricardo,Lucero Bryan,Lizárraga Pilar,Cieza Basilio,Roncal Elisa,Grandjean Louis,Pain Arnab,McNerney Ruth,Clark Taane G.,Moore David,Zimic Mirko^ORCID

Funder

Wellcome Trust

DFID-CSCF

The Joint Global Health Trials consortium

Imperial College Biomedical Research Centre

National Institutes of Health

TWAS

Grand Challenges Canada

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Biotechnology

Link

http://link.springer.com/content/pdf/10.1186/s12864-017-4146-z.pdf

Reference30 articles.

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3. Zhang Y, Scorpio A, Nikaido H, Sun Z. Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of mycobacterium tuberculosis to pyrazinamide. J Bacteriol. 1999;181:2044–9.

4. Konno K, Feldmann FM, McDermott W. Pyrazinamide susceptibility and amidase activity of tubercle bacilli. Am Rev Respir Dis. 1967;95:461–9.

5. Zhang Y, Wade MM, Scorpio A, Zhang H, Sun Z. Mode of action of pyrazinamide: disruption of mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. J Antimicrob Chemother. 2003;52:790–5.

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