A new pragmatic design for dose escalation in phase 1 clinical trials using an adaptive continual reassessment method
Author:
Funder
Medical Research Council
Cancer Research UK
Celgene
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Oncology
Link
http://link.springer.com/content/pdf/10.1186/s12885-019-5801-3.pdf
Reference37 articles.
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4. Goodman SN, Zahurak ML, Piantadosi S. Some practical improvements in the continual reassessment method for phase I studies. Stat Med. 1995;14(11):1149–61.
5. Babb J, Rogatko A, Zacks S. Cancer phase I clinical trials: efficient dose escalation with overdose control. Stat Med. 1998;17(10):1103–20.
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