Cancer-derived exosomes from HER2-positive cancer cells carry trastuzumab-emtansine into cancer cells leading to growth inhibition and caspase activation-Reference-Cited by-同舟云学术

Cancer-derived exosomes from HER2-positive cancer cells carry trastuzumab-emtansine into cancer cells leading to growth inhibition and caspase activation

Published:2018-05-02 Issue:1 Volume:18 Page:
ISSN:1471-2407
Container-title:BMC Cancer
language:en
Short-container-title:BMC Cancer

Author:

Barok Mark,Puhka Maija,Vereb Gyorgy,Szollosi Janos,Isola Jorma,Joensuu Heikki

Funder

Syöpäjärjestöt

Sigrid Juséliuksen Säätiö

Jane ja Aatos Erkon Säätiö

Academy of Finland

Research Funds of Helsinki University Hospital

SalWe Research Program Personalized Diagnostics and Care

National Research, Development and Innovation Office

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Oncology

Link

http://link.springer.com/content/pdf/10.1186/s12885-018-4418-2.pdf

Reference28 articles.

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2. Ritchie M, Tchistiakova L, Scott N. Implications of receptor-mediated endocytosis and intracellular trafficking dynamics in the development of antibody drug conjugates. MAbs. 2013;5:13–21.

3. Kovtun Y, Goldmacher V. Cell killing by antibody-drug conjugates. Cancer Lett. 2007;255:232–40.

4. Barok M, Joensuu H, Isola J. Trastuzumab emtansine: mechanisms of action and drug resistance. Breast Cancer Res. 2014;16(2):209.

5. Chari R. Targeted cancer therapy: conferring specificity to cytotoxic drugs. Acc Chem Res. 2008;41:98–107.

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