Prolonged use of human insulin increases breast cancer risk in Taiwanese women with type 2 diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Oncology
Link
http://link.springer.com/content/pdf/10.1186/s12885-015-1876-7.pdf
Reference46 articles.
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2. Tseng CH, Chong CK, Tai TY. Secular trend for mortality from breast cancer and the association between diabetes and breast cancer in Taiwan between 1995 and 2006. Diabetologia. 2009;52:240–6.
3. Radulescu RT. Intracellular insulin in human tumors: examples and implications. Diabetol Metab Syndr. 2011;3:5.
4. Dool CJ, Mashhedi H, Zakikhani M, David S, Zhao Y, Birman E, et al. IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer. Endocr Relat Cancer. 2011;18:699–709.
5. Fierz Y, Novosyadlyy R, Vijayakumar A, Yakar S, LeRoith D. Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes. Endocr Relat Cancer. 2010;17:941–51.
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