Translating genomic medicine to the clinic: challenges and opportunities-Reference-Cited by-同舟云学术

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Translating genomic medicine to the clinic: challenges and opportunities

Published:2019-02-22 Issue:1 Volume:11 Page:
ISSN:1756-994X
Container-title:Genome Medicine
language:en
Short-container-title:Genome Med

Author:

Zhang Huan,Klareskog Lars,Matussek Andreas,Pfister Stefan M.,Benson Mikael

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1186/s13073-019-0622-1.pdf

Reference10 articles.

1. Dzau VJ, Ginsburg GS, Van Nuys K, Agus D, Goldman D. Aligning incentives to fulfil the promise of personalised medicine. Lancet. 2015;385:2118–9.

2. Letai A. Functional precision cancer medicine—moving beyond pure genomics. Nat Med. 2017;23:1028.

3. Stranneheim H, Wedell A. Exome and genome sequencing: a revolution for the discovery and diagnosis of monogenic disorders. J Intern Med. 2016;279:3–15.

4. Le Tourneau C, Delord J-P, Gonçalves A, Gavoille C, Dubot C, Isambert N, et al. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial. Lancet Oncol. 2015;16:1324–34.

5. Tsherniak A, Vazquez F, Montgomery PG, Weir BA, Kryukov G, Cowley GS, et al. Defining a cancer dependency map. Cell. 2017;170:564–76.

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