Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis-Reference-Cited by-同舟云学术

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

Published:2017-03-09 Issue:1 Volume:9 Page:
ISSN:1756-994X
Container-title:Genome Medicine
language:en
Short-container-title:Genome Med

Author:

Swindell William R.,Michaels Kellie A.,Sutter Andrew J.,Diaconu Doina,Fritz Yi,Xing Xianying,Sarkar Mrinal K.,Liang Yun,Tsoi Alex,Gudjonsson Johann E.,Ward Nicole L.

Funder

American Skin Association

National Psoriasis Foundation

National Psoriasis Foudation

Babcock Endowment Fund

A. Alfred Taubman Medical Research Institute

National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1186/s13073-017-0415-3.pdf

Reference79 articles.

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2. Swindell WR, Johnston A, Carbajal S, Han G, Wohn C, Lu J, Xing X, Nair RP, Voorhees JJ, Elder JT, et al. Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. PLoS One. 2011;6:e18266.

3. van der Fits L, Mourits S, Voerman JS, Kant M, Boon L, Laman JD, Cornelissen F, Mus AM, Florencia E, Prens EP, Lubberts E. Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J Immunol. 2009;182:5836–45.

4. Flutter B, Nestle FO. TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis. Eur J Immunol. 2013;43:3138–46.

5. Pantelyushin S, Haak S, Ingold B, Kulig P, Heppner FL, Navarini AA, Becher B. Rorgammat + innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice. J Clin Invest. 2012;122:2252–6.

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