A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis-Reference-Cited by-同舟云学术

A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis

Published:2017-05-31 Issue:1 Volume:9 Page:
ISSN:1756-994X
Container-title:Genome Medicine
language:en
Short-container-title:Genome Med

Author:

Ross Colin J.,Towfic Fadi,Shankar Jyoti^ORCID,Laifenfeld Daphna,Thoma Mathis,Davis Matthew,Weiner Brian,Kusko Rebecca,Zeskind Ben,Knappertz Volker,Grossman Iris,Hayden Michael R.

Funder

Teva Pharmaceutical Industries (IL)

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1186/s13073-017-0436-y.pdf

Reference59 articles.

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2. International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet. 2013;45:1353–60. http://dx.doi.org/10.1038/ng.2770 .

3. International Multiple Sclerosis Genetics Consortium, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med. 2007;357:851–62. http://dx.doi.org/10.1056/NEJMoa073493 .

4. International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, Sawcer S, Hellenthal G, Pirinen M, Spencer CCA, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011;476:214–9. http://dx.doi.org/10.1038/nature10251 .

5. Bahlo M, Booth DR, Broadley SA, Brown MA, Foote SJ, Griffiths LR, et al. Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet. 2009;41:824–8. http://dx.doi.org/10.1038/ng.396 .

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