Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series-Reference-Cited by-同舟云学术

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Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

Published:2016-09-30 Issue:1 Volume:8 Page:
ISSN:1756-994X
Container-title:Genome Medicine
language:en
Short-container-title:Genome Med

Author:

Dumas Marc-Emmanuel,Domange Céline,Calderari Sophie,Martínez Andrea Rodríguez,Ayala Rafael,Wilder Steven P.,Suárez-Zamorano Nicolas,Collins Stephan C.,Wallis Robert H.,Gu Quan,Wang Yulan,Hue Christophe,Otto Georg W.,Argoud Karène,Navratil Vincent,Mitchell Steve C.,Lindon John C.,Holmes Elaine,Cazier Jean-Baptiste,Nicholson Jeremy K.,Gauguier Dominique

Funder

Sixth Framework Programme (BE)

Agence Nationale de la Recherche (FR)

Seventh Framework Programme (BE)

Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1186/s13073-016-0352-6.pdf

Reference59 articles.

1. Karlsson FH, Tremaroli V, Nookaew I, Bergström G, Behre CJ, Fagerberg B, et al. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature. 2013;498:99–103.

2. Dumas M-E. Metabolome 2.0: quantitative genetics and network biology of metabolic phenotypes. Mol Biosyst. 2012;8:2494–502.

3. Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert M-F, et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 2014;63:2158–71.

4. Yancey PH, Clark ME, Hand SC, Bowlus RD, Somero GN. Living with water stress: evolution of osmolyte systems. Science. 1982;217:1214–22.

5. Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, et al. Finding the missing heritability of complex diseases. Nature. 2009;461:747–53.

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