Clinical feasibility and preliminary outcomes of a novel mixed reality system to manage phantom pain: a pilot study

Abstract

Abstract Background To assess the clinical feasibility of a virtual mirror therapy system in a pilot sample of patients with phantom pain. Methods Our Mixed reality system for Managing Phantom Pain (Mr. MAPP) mirrors the preserved limb to visualize the amputated limb virtually and perform exercises. Seven patients with limb loss and phantom pain agreed to participate and received the system for 1-month home use. Outcome measures were collected at baseline and 1 month. Results Four (of seven recruited) participants completed the study, which was temporarily suspended due to COVID-19 restrictions. At 1 month, in-game data showed a positive trend, but pain scores showed no clear trends. Functioning scores improved for 1 participant. Conclusions Mr. MAPP is feasible and has the potential to improve pain and function in patients with phantom pain. Trial registration Clinical Trials Registration, NCT04529083