Author:
Makki Fawaz M,Rigby Matthew H,Bullock Martin,Brown Timothy,Hart Robert D,Trites Jonathan,Hinni Michael L,Taylor S Mark
Abstract
Abstract
Objective
To compare the suitability of CO2 laser with steel instruments for margin excision in transoral laser microsurgery.
Methods
Prospective randomized blinded study. Patients with glottic cancer undergoing laser resection were randomized to margin excision by either steel instruments or CO2 laser. Margins were analyzed for size, interpretability and degree of artifact by a pathologist who was blinded to technique.
Results
45 patients were enrolled in the study with 226 total margins taken. 39 margins taken by laser had marked artifact and 0 were uninterpretable. 20 margins taken by steel instruments had marked artifact, and 2 were uninterpretable. Controlling for margin size, the laser technique was associated with increasing degrees of margin artifact (p = 0.210), but there was no difference in crude rates of uninterpretability (p = 0.24).
Conclusion
Laser margin excision is associated with a greater degree of artifact than steel instrument excision, but was not associated with higher rate of uninterpretability.
Publisher
Springer Science and Business Media LLC
Subject
Otorhinolaryngology,Surgery
Cited by
18 articles.
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