Are large clinical trials in orthopaedic trauma justified?-Reference-Cited by-同舟云学术

Are large clinical trials in orthopaedic trauma justified?

Published:2018-04-20 Issue:1 Volume:19 Page:
ISSN:1471-2474
Container-title:BMC Musculoskeletal Disorders
language:en
Short-container-title:BMC Musculoskelet Disord

Author:

Sprague Sheila, ,Tornetta Paul,Slobogean Gerard P.,O’Hara Nathan N.,McKay Paula,Petrisor Brad,Jeray Kyle J.,Schemitsch Emil H.,Sanders David,Bhandari Mohit

Funder

Canadian Institutes of Health Research

U.S. Army Institute of Surgical Research

Orthopaedic Trauma Research Program

Peer Reviewed Orthopaedic Research Program

Association Internationale pour l’Ostéosynthèse Dynamique

Stryker

Zimmer

Triad Medical

Publisher

Springer Science and Business Media LLC

Subject

Orthopedics and Sports Medicine,Rheumatology

Link

http://link.springer.com/content/pdf/10.1186/s12891-018-2029-3.pdf

Reference9 articles.

1. Hilibrand AS, Spindler K, O'Keefe RJ. Demonstrating the value of orthopaedic surgery through multicenter trials: AOA critical issues. J Bone Joint Surg Am. 2015;97:e35.

2. Ioannidis JP. Contradicted and initially stronger effects in highly cited clinical research. JAMA. 2005;294:218–28.

3. SPRINT Investigators, Bhandari M, Tornetta P 3rd, Rampersad SA, Sprague S, Heels-Ansdell D, et al. (Sample) size matters! An examination of sample size from the SPRINT trial study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures. J Orthop Trauma. 2013;27:183–8.

4. FLOW Investigators. Fluid lavage of open wounds (FLOW): design and rationale for a large, multicenter collaborative 2 x 3 factorial trial of irrigating pressures and solutions in patients with open fractures. BMC Musculoskelet Disord. 2010;11:85.

5. FLOW Investigators. A trial of wound irrigation in the initial management of open fracture wounds. N Engl J Med. 2015;373:2629–41.

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3. CORR Insights®: Discordance Abounds in Minimum Clinically Important Differences in THA: A Systematic Review;Clinical Orthopaedics & Related Research;2023-02-02

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