Phytochemical comparison and evaluation of anti-inflammatory and anti-diabetic activity of three source plants of Jivanti-an important Ayurvedic drug

Author:

C. T. Sulaiman,C. K. Jyothi,G. Jinu Krishnan Unnithan,K. M. Prabhukumar,Balachandran Indira

Abstract

Abstract Background In Ayurveda, Jivanti is an important Rasayana drug that increases the energy level of the body. The botanical source of Jivanti is in a situation of controversy. The root of Leptadenia reticulata is the genuine source plant for Jivanti as per Ayurvedic Pharmacopeia of India. However, other species such as Holostemma ada-kodien and Flickingeria nodosa are also used as source plants for Jivanti in various parts of the country. The objective of this study is to identify a scientifically validated alternative source plant for Jivanti by phytochemical and pharmacological evaluation. Results In this study, anti-inflammatory and anti-diabetic activities of various source plants for Jivanti were evaluated along with their phytochemical comparison. H. ada-kodien showed significant anti-inflammatory and anti-diabetic activity when compared to L. reticulata. Conclusion The study concluded the possibility of using Holostemma ada-kodien as a substitute for Jivanti in the Ayurvedic drug industry. Graphical abstract

Funder

National Medicinal Plants Board, Ministry of AYUSH, Government of India

Publisher

Springer Science and Business Media LLC

Reference31 articles.

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