Fusion of green fluorescent protein to the C-terminus of granulysin alters its intracellular localization in comparison to the native molecule

Author:

Hanson Dennis A,Ziegler Steven F

Publisher

Springer Science and Business Media LLC

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference7 articles.

1. Patterson GH, Knobel SM, Sharif WD, Kain SR, Piston DW: Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy. Biophys J. 1997, 73: 2782-2790.

2. Kaether C, Salm T, Glombik M, Almers W, Gerdes HH: Targeting of green fluorescent protein to neuroendocrine secretory granules: a new tool for real time studies of regulated protein secretion. Eur J Cell Biol. 1997, 74: 133-142.

3. Russell JH, Ley TJ: Lymphocyte-mediated Cytotoxicity. Ann Rev Immunol. 2002, 20: 323-370. 10.1146/annurev.immunol.20.100201.131730.

4. Page LJ, Darmon AJ, Uellner R, Griffiths GM: L is for lytic granules: lysosomes that kill. Biochim Biophys Acta. 1998, 1401: 146-156. 10.1016/S0167-4889(97)00138-9.

5. Pena SV, Hanson DA, Carr BA, Goralski TJ, Krensky AM: Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins. J Immunol. 1997, 158: 2680-2688.

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