Author:
Tang Xueyao,Hu Yifan,Zhou Hong,Zhou Yang
Abstract
Abstract
Background
Testicular Sertoli cell tumor (SCT) is very rare sex cord-gonadal stromal tumor, and sclerosing SCT (SSCT) is even rarer. So far, no more than 50 cases of SSCT have been reported. 80% of SSCTs are less than 2 cm in diameter, large volume mass is pretty unusual. SSCT is usually benign with very low malignant potential. However, it is easily misdiagnosed as a malignant tumor resulting in the removal of the entire testicle.
Case presentation
A 55-year-old Chinese male patient presented with a six months’ history of right testis progressively enlargement and negative tumor markers. The physical examination was nothing special except for swelling in the right testicle. Imaging identified a large mass in right testicle with rich blood. A right radical orchiectomy was performed on suspicion of malignancy. However, the tumor was postoperatively diagnosed as SSCT, which pathologically consisted of a tubular pattern with regular nuclei and embedded in a densely collagenous stroma, as well as diffusely positive for vimentin, β-catenin and synaptophysin. After 7 months of follow up, no evidence of local recurrence and metastasis has been observed.
Conclusion
This rare case is helpful to expand the knowledge of the testicular tumor and alert us fully understand the rare variant of SCTs in order to choose the optimal management when they encounter SSCT.
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Histology,Pathology and Forensic Medicine
Reference16 articles.
1. Golombos D, Brison D, Sadeghi-Nejad H. Malignant sertoli cell tumor of the testis with a large retroperitoneal mass in an elderly man. Urol J. 2010;7(4):281–3.
2. Song DH, Jeong SM, Park JT, Yun GW, Kim BK, Lee JS. Large cell calcifying sertoli cell tumor of the testis: a case study and review of the literature. Korean J Pathol. 2014;48(1):50–3.
3. Zukerberg LR, Young RH, Scully RE. Sclerosing sertoli cell tumor of the testis. A report of 10 cases. Am J Surg Pathol. 1991;15(9):829–34.
4. Kao CS, Kum JB, Idrees MT, Ulbright TM. Sclerosing sertoli cell tumor of the Testis A Clinicopathologic Study of 20 cases. Am J Surgpathol. 2014;38(4):510–7.
5. Abbas F, Bashir NW, Hussainy AS. Sclerosing sertoli cell tumor of the testis. J Coll Physicians Surg Pak. 2005;15(7):437–8.