Author:
Liu Rui,Li Jing,Ren Tingting,Zhang Hong,Ma Jianmin
Abstract
Abstract
Background
Eosinophilic angiocentric fibrosis (EAF) is a rare inflammatory lesion, especially in orbit. EAF is believed to be related to IgG4-related disease (IgG4-RD), but the clinical manifestations of systemic involvement are relatively rare and easy to be confused with tumors or other inflammatory diseases. Histopathological examination is the most important way of its diagnosis and differentiation.
Case presentation
We presented a 55-year-old female patient presented with recurrent swelling of the right lower eyelid for more than 2 months. The pathological diagnosis was EAF. Positive immunostaining for IgG, CD34, κ, and λ, while negative immunostaining for IgG4.
Conclusions
Complete surgical resection is the preferred treatment, histopathological examination is the main diagnostic standard.
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Histology,Pathology and Forensic Medicine
Reference20 articles.
1. Javadirad E, Roozbahani NE, Sadafi S. Eosinophilic angiocentric fibrosis of the sinonasal tract: a case report and review of the literature. J Int Med Res. 2022;50(9):3000605221126039. https://doi.org/10.1177/03000605221126039.
2. Daneshi SA, Taheri M, Fattahi A, Fadavi P. The primary brain eosinophilic angiocentric fibrosis, a rare case report. Prague Med Rep. 2022;123(2):113–9. https://doi.org/10.14712/23362936.2022.12.
3. Saenz-Ibarra B, Ceceñas-Falcon LA, Cardenas-De la Garza JA, Garza-Elizondo MA, De Hoyos R, Dieste M, et al. Nasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration. Malays J Pathol. 2020;42(1):137–41.
4. Chew EJC, Lee MH, Chung HW, Tang PY. Eosinophilic angiocentric fibrosis and immunoglobulin 4-related disease revisited. Histopathology. 2022;81(2):149–58. https://doi.org/10.1111/his.14646.
5. Heedari HM, Ciotoracu AC, Mitulescu TC, Dimancescu MG, Enache S, Predețeanu D. A clinical case of orbital inflammatory pseudotumor as the primary expression of eosinophilic angiocentric fibrosis. Rom J Ophthalmol. 2021;65(4):411–8. https://doi.org/10.22336/rjo.2021.82.
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