Therapeutic application of adipose-derived stromal vascular fraction in diabetic foot-Reference-Cited by-同舟云学术

Therapeutic application of adipose-derived stromal vascular fraction in diabetic foot

Published:2020-09-14 Issue:1 Volume:11 Page:
ISSN:1757-6512
Container-title:Stem Cell Research & Therapy
language:en
Short-container-title:Stem Cell Res Ther

Author:

Zhao Xiansheng,Guo Jiamin,Zhang Fangfang,Zhang Jue,Liu Delin,Hu Wenjun,Yin Han,Jin Liang

Abstract

AbstractDiabetic foot is one of the severest complications of diabetes. In severe cases, this disease may be lead to amputation or even death due to secondary infection and ischemic necrosis. Since the ineffectiveness of traditional therapy, autologous stem cell transplantation has been used to treat diabetic foot. This simple, safe, and effective therapy is expected to be applied and promoted in the future.In this review, we described the detailed pathogenesis of diabetic foot and the common clinical treatments currently used. We also revealed vascular remodeling as the potential mechanism of therapeutic functions of adipose-derived stromal vascular fraction (SVF) in treating diabetic foot.

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Medicine,Medicine (miscellaneous)

Link

https://link.springer.com/content/pdf/10.1186/s13287-020-01825-1.pdf

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