High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection

Author:

Dobaño CarlotaORCID,Berthoud Tamara,Manaca Maria Nelia,Nhabomba Augusto,Guinovart Caterina,Aguilar Ruth,Barbosa Arnoldo,Groves Penny,Rodríguez Mauricio H.,Jimenez Alfons,Quimice Lazaro M.,Aponte John J.,Ordi Jaume,Doolan Denise L.,Mayor Alfredo,Alonso Pedro L.

Funder

FP6 EU

Ministerio de Ciencia e Innovación

Instituto de Salud Carlos III

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Parasitology

Reference52 articles.

1. World Health Organization. World Malaria Report 2017. 2017. http://www.who.int/malaria/publications/world-malaria-report-2017/en/ . Accessed 14 Dec 2017.

2. Ismail MR, Ordi J, Menendez C, Ventura PJ, Aponte JJ, Kahigwa E, et al. Placental pathology in malaria: a histological, immunohistochemical, and quantitative study. Hum Pathol. 2000;31:85–93.

3. Fried M, Muga RO, Misore AO, Duffy PE. Malaria elicits type 1 cytokines in the human placenta: IFN-gamma and TNF-alpha associated with pregnancy outcomes. J Immunol. 1998;160:2523–30.

4. Mor G, Cardenas I. The immune system in pregnancy: a unique complexity. Am J Reprod Immunol. 2010;63:425–33.

5. Rogerson SJ, Hviid L, Duffy PE, Leke RF, Taylor DW. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis. 2007;7:105–17.

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