Assessing the impact of the “malaria supporters project” intervention to malaria control in the Brazilian Amazon: an interrupted time-series analysis
-
Published:2023-09-16
Issue:1
Volume:22
Page:
-
ISSN:1475-2875
-
Container-title:Malaria Journal
-
language:en
-
Short-container-title:Malar J
Author:
Garcia Klauss Kleydmann Sabino,Soremekun Seyi,Bottomley Christian,Abrahão Amanda Amaral,de Miranda Cristiano Barreto,Drakeley Chris,Ramalho Walter Massa,Siqueira André M.
Abstract
Abstract
Background
In 2021, Brazil was responsible for more than 25% of malaria cases in the Americas. Although the country has shown a reduction of cases in the last decades, in 2021 it reported over 139,000 malaria cases. One major malaria control strategy implemented in Brazil is the “Malaria Supporters Project”, which has been active since 2012 and is directed to municipalities responsible for most Brazil’s cases. The objective of this study is to analyse the intervention effect on the selected municipalities.
Methods
An ecological time-series analysis was conducted to assess the “Malaria Supporters Project” effect. The study used data on Annual Parasitic Incidence (API) spanning the period from 2003 to 2020 across 48 intervention municipalities and 88 control municipalities. To evaluate the intervention effect a Prais–Winsten segmented regression model was fitted to the difference in malaria Annual Parasitic Incidence (API) between control and intervention areas.
Results
The intervention group registered 1,104,430 cases between 2012 and 2020, a 50.6% reduction compared to total cases between 2003 and 2011. In 2020 there were 95,621 cases, 50.4% fewer than in 2011. The number of high-risk municipalities (API > 50 cases/1000) reduced from 31 to 2011 to 17 in 2020. The segmented regression showed a significant 42.0 cases/1000 residents annual decrease in API compared to control group.
Conclusions
The intervention is not a silver bullet to control malaria, but it has reduced API in locations with high malaria endemicity. Furthermore, the model has the potential to be replicated in other countries with similar epidemiological scenarios.
Funder
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Bill and Melinda Gates Foundation
Ministério da Saúde
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Parasitology
Reference40 articles.
1. WHO. World malaria report 2022. Geneva: World Health Organization; 2022.
2. Duarte EC, Ramalho WM, Tauil PL, Fontes CJ, Pang L. The changing distribution of malaria in the Brazilian Amazon, 2003–2004 and 2008–2009. Rev Soc Bras Med Trop. 2014;47:763–9.
3. Oliveira-Ferreira J, Lacerda MV, Brasil P, Ladislau JL, Tauil PL, Daniel-Ribeiro CT. Malaria in Brazil: an overview. Malar J. 2010;9:115.
4. Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Panorama epidemiológico da malária em 2021: buscando o caminho para a eliminação da malária no Brasil. Epidemiological bulletin 2022. https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/edicoes/2022/boletim-epidemiologico-vol-53-no17.pdf. Accessed 13 Mar 2023.
5. Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Articulação Estratégica de Vigilância em Saúde. Guia de Vigilância em Saúde, 5th edition. Brasilia; 2022.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献