Abstract
AbstractBurundi has experienced an increase in malaria cases since 2000, reaching 843,000 cases per million inhabitants in 2019, a more than twofold increase compared to the early 2000s. Burundi thus contrasts the decreasing number of cases in many other African countries. To evaluate the impact of malaria control on this increase, data on interventions from 2000 to 2019 were compiled. Over this period, the number of health facilities increased threefold, and the number of tests 20-fold. The test positivity rate remained stable at around 50–60% in most years. Artemisinin-based combination therapy was introduced in 2003, initially using artesunate–amodiaquine and changed to artemether–lumefantrine in 2019/2020. Mass distribution campaigns of insecticide-treated bed nets were conducted, and indoor residual spraying and intermittent preventive treatment in pregnancy introduced. Thus, the increase in cases was not the result of faltering control activities. Increased testing was likely a key contributor to higher case numbers. Despite the increase in testing, the test positivity rate remined high, indicating that current case numbers might still underestimate the true burden.
Funder
National Institute of Allergy and Infectious Diseases
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Parasitology
Reference33 articles.
1. Delacollette C, Barutwanayo M. Mortality and morbidity at young ages in a stable hyperendemic malaria region, community Nyanza-Lac, Imbo South, Burundi. Bull Soc Pathol Exot. 1993;86:373–9 (in French).
2. Rowe AK, Rowe SY, Snow RW, Korenromp EL, Schellenberg JRA, Stein C, et al. The burden of malaria mortality among African children in the year 2000. Int J Epidemiol. 2006;35:691–704.
3. Lok P, Dijk S. Malaria outbreak in Burundi reaches epidemic levels with 5.7 million infected this year. BMJ. 2019;366:l5104.
4. Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, et al. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature. 2015;526:207–11.
5. Republique du Burundi. Ministère de santé publique et de la lutte contre le SIDA, Direction generale de la planification direction du systeme national d’information sanitaire. Plan Stratégique d’amélioration de la qualité des données du système national d’information sanitaire 2019–2023. Bujumbura; 2018.
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