Rapid clinical improvement of amyloid A amyloidosis following treatment with tocilizumab despite persisting amyloid deposition: a case report

Author:

Yamagata AkiraORCID,Uchida Takahiro,Yamada Yuji,Nakanishi Takashi,Nagai Kazue,Imakiire Toshihiko,Oshima Naoki,Kumagai Hiroo

Publisher

Springer Science and Business Media LLC

Subject

Nephrology

Reference16 articles.

1. Falk RH, Comezo RL, Skinner M. The systemic amyloidosis. N Engl J Med. 1997;337:898–909.

2. Obici L, Raimondi S, Lavetelli F, Bellotti V, Merlini G. Susceptibility to AA amyloidosis in rheumatic disease: a critical overview. Arthritis Rheum. 2009;61:1435–40.

3. Nakamura T. Amyloid a amyloidosis secondary to rheumatoid arthritis: pathophysiology and treatment. Clin Exp Rheumatol. 2011;29:850–7.

4. Matsui M, Okayama S, Tsushima H, Samejima K, Kanki T, Hasegawa A, et al. Therapeutic benefits of tocilizumab vary in different organs of a patient with AA amyloidosis. Case Rep Nephrol. 2014;2014:823093.

5. Miyagawa I, Nakayamada S, Saito K, Hanami K, Nawata M, Sawamukai N, et al. Study on the safety and efficacy of tocilizumab, an anti-IL-6 receptor antibody, in patients with rheumatoid arthritis complicated with AA amyloidosis. Mod Rheumatology. 2014;24:405–9.

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