Author:
Taha Hesham Salah El Din,Badran Hala Mahfouz,Kandil Hossam,Farag Nabil,Oraby Abbas,El Sharkawy Magdy,Shokry Khaled,Fawzy Fouad,Mahrous Hossam,Bahgat Juliette,Samy Mina,Shaker Mirna Mamdouh
Abstract
Abstract
Background
Numerous epidemiological investigations and randomized clinical studies have determined that dyslipidemia is a major contributor to atherosclerotic cardiovascular disease (ASCVD). Consequently, the management of serum cholesterol and low-density lipoprotein levels has become a central objective in the effort to prevent cardiovascular events.
Main body
Many guidelines were issued by different organizations and societies to define patient risk and establish important recommendations for management strategies. Newer cholesterol-lowering agents (non-statin drugs) are described, and their use is directed primarily to secondary prevention in patients at very high risk of new ASCVD.
Conclusion
The present guidance summarizes the current methods for risk estimation and outlines the most recent data on lipid management in a simple user-friendly format, to improve physician awareness and help implement guidelines in the daily practice.
Publisher
Springer Science and Business Media LLC
Reference33 articles.
1. Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L et al (2020) 2019 ESC/EAS Guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk. European Heart Journal 41(1):111–188
2. Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N et al (2010) Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials. Lancet. 376(9753):1670–1681
3. Michos ED, McEvoy JW, Blumenthal RS (2019) Lipid management for the prevention of atherosclerotic cardiovascular disease. The New England Journal of Medicine 381(16):1557–1567
4. Reda A, Abdel-Rehim AA, Etman A, Afifi OSA (2014) Centralized pan-Middle East Survey on the under-treatment of hypercholesterolemia: results from the CEPHEUS study in Egypt. Cardiol Ther. 3(1–2):27–40
5. Farag ES, Reda A, Farag N, Salama S, Elbahry A, Sanad O et al (2017) The Egyptian cardiovascular risk factors project, phase (II) results: a multicenter observational study of the pattern of risk factor profile in Egyptian patients with acute coronary syndrome. Atherosclerosis. 263:e159
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