MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma

Author:

Vella Serena,Pomella Silvia,Leoncini Pier Paolo,Colletti Marta,Conti Beatrice,Marquez Victor E.,Strillacci Antonio,Roma Josep,Gallego Soledad,Milano Giuseppe M.,Capogrossi Maurizio C.,Bertaina Alice,Ciarapica Roberta,Rota Rossella

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Developmental Biology,Genetics,Molecular Biology

Reference37 articles.

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2. Puri PL, Wu Z, Zhang P, Wood LD, Bhakta KS, Han J, et al. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev. 2000;14:574–84.

3. Wang H, Garzon R, Sun H, Ladner KJ, Singh R, Dahlman J, et al. NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell. 2008;14:369–81.

4. Taulli R, Bersani F, Foglizzo V, Linari A, Vigna E, Ladanyi M, et al. The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. J Clin Invest. 2009;119:2366–78.

5. Caretti G, Di Padova M, Micales B, Lyons GE, Sartorelli V. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev. 2004;18:2627–38.

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