Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes

Author:

Habano Wataru,Kawamura Kohei,Iizuka Natsuki,Terashima Jun,Sugai Tamotsu,Ozawa Shogo

Funder

Grant-in Aid for Scientific Research (C)

Grant-in-Aid for Strategic Medical Science Research Center

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Developmental Biology,Genetics,Molecular Biology

Reference30 articles.

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3. Scott SA, Sangkuhl K, Shuldiner AR, Hulotn J-S, Thorn CF, Altman RB, et al. PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19. Pharmacogenet Genomics. 2012;22:159–65.

4. Owen RP, Sangkuhl K, Klein TE, Altman RB. Cytochrome P450 2D6. Pharmacogenet Genomics. 2009;19:559–62.

5. Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich P. Inter-individual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther. 1994;270:414–23.

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