Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk

Author:

Johansson Annelie,Palli Domenico,Masala Giovanna,Grioni Sara,Agnoli Claudia,Tumino Rosario,Giurdanella Maria Concetta,Fasanelli Francesca,Sacerdote Carlotta,Panico Salvatore,Mattiello Amalia,Polidoro Silvia,Jones Michael E.,Schoemaker Minouk J.,Orr Nick,Tomczyk Katarzyna,Johnson Nichola,Fletcher Olivia,Perduca Vittorio,Baglietto Laura,Dugué Pierre-Antoine,Southey Melissa C.,Giles Graham G.,English Dallas R.,Milne Roger L.,Severi Gianluca,Ambatipudi Srikant,Cuenin Cyrille,Chajès Veronique,Romieu Isabelle,Herceg Zdenko,Swerdlow Anthony J.,Vineis Paolo,Flanagan James M.ORCID

Funder

Breast Cancer Now

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Developmental Biology,Genetics,Molecular Biology

Reference45 articles.

1. International Agency for Research on Cancer. EPIC study. 2018. http://epic.iarc.fr . Accessed: September 2018.

2. Eccles SA, Aboagye EO, Ali S, Anderson AS, Armes J, Berditchevski F, et al. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast cancer research: BCR. 2013;15(5):R92.

3. Cancer Research UK. Breast cancer statistics 2018. https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/breast-cancer . Accessed: November 2018.

4. Endogenous Hormones Breast Cancer Collaborative Group. Circulating sex hormones and breast cancer risk factors in postmenopausal women: reanalysis of 13 studies. Br J Cancer. 2011;105(5):709–22.

5. Endogenous Hormones Breast Cancer Collaborative Group. Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies. Lancet Oncol. 2013;14(10):1009–19.

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