The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility

Author:

Watanabe Susan M.,Simon Viviana,Durham Natasha D.,Kemp Brittney R.,Machihara Satoshi,Kemal Kimdar Sherefa,Shi Binshan,Foley Brian,Li Hongru,Chen Benjamin K.,Weiser Barbara,Burger Harold,Anastos Kathryn,Chen Chaoping,Carter Carol A.

Funder

NIH NIAID

National Institute of General Medical Sciences

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology

Reference48 articles.

1. Adamson CS, Sakalian M, Salzwedel K, Freed EO. Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV-1 maturation inhibitor bevirimat. Retrovirology. 2010;7:36.

2. Lefebvre E, Schiffer CA. Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir. AIDS Rev. 2008;10:131–42.

3. Wensing AM, van Maarseveen NM, Nijhuis M. Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance. Antiviral Res. 2010;85:59–74.

4. Fun A, Wensing AM, Verheyen J, Nijhuis M. Human immunodeficiency virus Gag and protease: partners in resistance. Retrovirology. 2012;9:63.

5. Brumme ZL, Chan KJ, Dong WW, Wynhoven B, Mo T, Hogg RS, Montaner JS, O’Shaughnessy MV, Harrigan PR. Prevalence and clinical implications of insertions in the HIV-1 p6Gag N-terminal region in drug-naive individuals initiating antiretroviral therapy. Antivir Ther. 2003;8:91–6.

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