Author:
Pelucchi Claudio,Negri Eva,Gallus Silvano,Boffetta Paolo,Tramacere Irene,La Vecchia Carlo
Abstract
Abstract
Background
Several studies considered the relation between long-term exposure to particulate matter (PM) and total mortality, as well as mortality from cardiovascular and respiratory diseases. Our aim was to provide a comprehensive review of European epidemiological studies on the issue.
Methods
We searched the Medline database for epidemiological studies on air pollution and health outcomes published between January 2002 and December 2007. We also examined the reference lists of individual papers and reviews. Two independent reviewers classified the studies according to type of air pollutant, duration of exposure and health outcome considered. Among European investigations that examined long-term PM exposure we found 4 cohort studies (considering total and cardiopulmonary mortality), 1 case-control study (considering mortality from myocardial infarction), and 4 ecologic studies (2 studies considering total and cardiopulmonary mortality and 2 studies focused on cardiovascular mortality).
Results
Measurement indicators of PM exposure used in European studies, including PM10, PM2.5, total suspended particulate and black smoke, were heterogeneous. This notwithstanding, in all analytic studies total mortality was directly associated with long-term exposure to PM. The excesses in mortality were mainly due to cardiovascular and respiratory causes. Three out of 4 ecologic studies found significant direct associations between PM indexes and mortality.
Conclusion
European studies on long-term exposure to PM indicate a direct association with mortality, particularly from cardiovascular and respiratory diseases.
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health
Reference26 articles.
1. US EPA: Air quality criteria for particulate matter. US Environmental Protection Agency, Research Triangle Park, NC, 2004. Document EPA/600/P-99/002aF, II: [http://cfpub2.epa.gov/ncea/cfm/recordisplay.cfm?deid=87903]
2. Pope CA, Burnett RT, Thun MJ, Calle EE, Krewski D, Ito K, Thurston GD: Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA. 2002, 287 (9): 1132-1141. 10.1001/jama.287.9.1132.
3. Laden F, Schwartz J, Speizer FE, Dockery DW: Reduction in fine particulate air pollution and mortality: Extended follow-up of the Harvard Six Cities study. Am J Respir Crit Care Med. 2006, 173 (6): 667-672. 10.1164/rccm.200503-443OC.
4. Miller KA, Siscovick DS, Sheppard L, Shepherd K, Sullivan JH, Anderson GL, Kaufman JD: Long-term exposure to air pollution and incidence of cardiovascular events in women. N Engl J Med. 2007, 356 (5): 447-458. 10.1056/NEJMoa054409.
5. Gallus S, Negri E, Boffetta P, McLaughlin JK, Bosetti C, La Vecchia C: European studies on long-term exposure to ambient particulate matter and lung cancer. Eur J Cancer Prev. 2008, 17 (3): 191-194. 10.1097/CEJ.0b013e3282f0bfe5.
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