Bilateral anterior and intermediate uveitis in SARS-CoV-2 associated multisystem inflammatory syndrome in a pediatric patient

Author:

Shantha JessicaORCID,Reddy Amit K.,Sura Amol,Tsang Adrian,Moussa Kareem,Acharya Nisha,Gonzales John,Doan Thuy

Abstract

Abstract Purpose To report a case of bilateral anterior intermediate uveitis after recovery from SARS-CoV-2 associated multisystem inflammatory syndrome in children (MIS-C). Case Report A 9-year-old male presented with bilateral anterior intermediate uveitis with fluorescein angiography (FA) leakage of the disc and peripheral vasculature 1 month after recovery from MIS-C. He was treated with difluprednate 0.05% in both eyes with resolution of FA leakage, but our patient has required an extended treatment of topical therapy and the need long term immunosuppression. Conclusions This is a case of uveitis presenting after recent MIS-C related to SARS-CoV-2. Ongoing follow up and monitoring is required, and it is important for the ophthalmologist and rheumatologist to be aware of this rare complication during the current COVID-19 pandemic.

Funder

National Eye Institute

Publisher

Springer Science and Business Media LLC

Subject

Immunology and Allergy,Rheumatology,Pediatrics, Perinatology and Child Health

Reference8 articles.

1. Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, Son MBF, Tremoulet AH, Yeung RSM, Mudano AS, Turner AS, Karp DR, Mehta JJ. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 2. Arthritis Rheumatol. 2021 Apr;73(4):e13–29. doi:https://doi.org/10.1002/art.41616. Epub 2021 Feb 15. PMID: 33277976.

2. Feng Y, Armenti ST, Mian SI. COVID-19 and the Eye: A Comprehensive Review of the Literature. Int Ophthalmol Clin. 2021;61(1):1–14. https://doi.org/10.1097/IIO.0000000000000339 PMID: 33337790.

3. Karthika IK, Gulla KM, John J, Satapathy AK, Sahu S, Behera B, Mishra P. COVID-19 related multi-inflammatory syndrome presenting with uveitis - A case report. Indian J Ophthalmol. 2021 May;69(5):1319–21. doi:https://doi.org/10.4103/ijo.IJO_52_21. PMID: 33913889; PMCID: PMC8186627.

4. Wong Chung JERE, Engin Ö, Wolfs TFW, Renson TJC, de Boer JH. Anterior uveitis in paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. Lancet. 2021;397;10281. https://doi.org/10.1016/S0140-6736(21)00579-1. PMID: 33812491; PMCID: PMC8016403

5. Öztürk C, Yüce Sezen A, Savaş Şen Z, Özdem S. Bilateral Acute Anterior Uveitis and Corneal Punctate Epitheliopathy in Children Diagnosed with Multisystem Inflammatory Syndrome Secondary to COVID-19. Ocul Immunol Inflamm. 2021;29(4):700–4. https://doi.org/10.1080/09273948.2021.1909070 Epub 2021 Apr 15 PMID: 33856952.

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3