Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos-Reference-Cited by-同舟云学术

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Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos

Published:2019-05-06 Issue:1 Volume:19 Page:
ISSN:1472-6750
Container-title:BMC Biotechnology
language:en
Short-container-title:BMC Biotechnol

Author:

Carey Kayla,Ryu Junghyun,Uh Kyungjun,Lengi Andrea J.,Clark-Deener Sherrie,Corl Benjamin A.,Lee Kiho

Funder

Virginia Agricultural Experiment Station, Virginia Polytechnic Institute and State University

Publisher

Springer Science and Business Media LLC

Subject

Biotechnology

Link

http://link.springer.com/content/pdf/10.1186/s12896-019-0517-7.pdf

Reference32 articles.

1. Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, Christian M, Voytas DF, Long CR, Whitelaw CB, Fahrenkrug SC. Efficient TALEN-mediated gene knockout in livestock. Proc Natl Acad Sci U S A. 2012;109(43):17382–7.

2. Yang D, Yang H, Li W, Zhao B, Ouyang Z, Liu Z, Zhao Y, Fan N, Song J, Tian J, et al. Generation of PPARgamma mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Res. 2011;21(6):979–82.

3. Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, et al. Multiplex Genome Engineering Using CRISPR/Cas Systems. Science (New York, NY). 2013;339(6121):819–23.

4. Gaj T, Gersbach CA, Barbas CF, 3rd: ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 2013, 31(7):397–405.

5. Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD. High frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat Biotechnol. 2013;31(9):822–6.

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1. Tackling hepatitis B Virus with CRISPR/Cas9: advances, challenges, and delivery strategies;Virus Genes;2024-08-28

2. Germline genome editing of human IVF embryos should not be subject to overly stringent restrictions;Journal of Assisted Reproduction and Genetics;2024-07

3. Novel off-Targeting Events Identified after Genome Wide Analysis of CRISPR-Cas Edited Pigs;The CRISPR Journal;2024-06-01

4. Genome Engineering in Livestock: Recent Advances and Regulatory Framework;Animal Reproduction Update;2022-12-22

5. Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in Animals;Veterinary Research Communications;2022-07-04

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