Comprehensive bibliometric and visualized analysis of research on fecal microbial transplantation published from 2000 to 2021
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Published:2022-10-29
Issue:1
Volume:21
Page:
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ISSN:1475-925X
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Container-title:BioMedical Engineering OnLine
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language:en
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Short-container-title:BioMed Eng OnLine
Author:
Ma Jing,Chen Ting,Ma Xiangxue,Zhang Beihua,Zhang Jiaqi,Xu Lin,Wang Yifan,Huang Jinke,Liu Zhihong,Wang Fengyun,Tang Xudong
Abstract
Abstract
Background
Fecal microbial transplantation has emerged in recent years as a method of treating disease by rebuilding the intestinal flora. However, few bibliometric analyses have systematically studied this area of research. We aimed to use bibliometric analysis to visualize trends and topical research in fecal microbial transplantation to help provide insight into future trends in clinical and basic research.
Materials and methods
Articles and reviews related to fecal microbial transplantation were collected from the Web of Science Core Collection. Significant information associated with this field was visually analyzed by using Biblioshiny and CtieSpace software.
Results
A total of 3144 articles and overviews were included. The number of publications related to fecal microbial transplantation significantly increased yearly. These publications mainly came from 100 countries, led by the US and China, and 521 institutions. The most prolific and influential author is KHORUTS A. The main disciplines and application fields of fecal microbial transplantation included molecular /biology/immunology and medicine/clinical medicine, and the research foundation of fecal microbial transplantation was molecular /biology/genetics and health/nursing/medicine. An alluvial flow visualization showed several landmark articles. New developments were identified in terms of reference and keyword citation bursts. Data analysis showed that different FMT preparation and delivery methods gradually appeared as research hotspots. The main research keywords in the last 3 years were chain fatty acids, Akkermansia muciniphila, and insulin sensitivity, other keywords were current and developing research fields.
Conclusion
Research on fecal microbial transplantation is flourishing and many new applications of fecal microbial transplantation are emerging. Microbial metabolites such as short-chain fatty acids and the microbiota–gut–brain axis have become the focus of current research and are future research trends.
Funder
National Natural Science Foundation of China
Young Elite Scientists Sponsorship Program by CAST
China Academy of Chinese Medical Sciences Innovation Fund
Inheritance and innovation team of Traditional Chinese Medicine for the treatment of Refractory Gastrointestinal Diseases
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging,Biomedical Engineering,General Medicine,Biomaterials,Radiological and Ultrasound Technology
Cited by
2 articles.
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