Appropriate use of triazolam in elderly patients considering a quantitative benefit-risk assessment based on the pharmacokinetic-pharmacodynamic modeling and simulation approach supported by real-world data
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1186/s40360-024-00777-z.pdf
Reference41 articles.
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3. Schlender JF, Meyer M, Thelen K, Krauss M, Willmann S, Eissing T, et al. Development of a whole-body physiologically based Pharmacokinetic Approach to assess the pharmacokinetics of drugs in Elderly individuals. Clin Pharmacokinet. 2016;55(12):1573–89.
4. Gutiérrez-Valencia M, Izquierdo M, Malafarina V, Alonso-Renedo J, González-Glaría B, Larrayoz-Sola B, et al. Impact of hospitalization in an acute geriatric unit on polypharmacy and potentially inappropriate prescriptions: a retrospective study. Geriatr Gerontol Int. 2017;17(12):2354–60.
5. Kojima T, Akishita M, Kameyama Y, Yamaguchi K, Yamamoto H, Eto M, et al. High risk of adverse drug reactions in elderly patients taking six or more drugs: analysis of inpatient database. Geriatr Gerontol Int. 2012;12(4):761–2.
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