Effect of CYP3 A4, CYP3 A5 and ABCB1 gene polymorphisms on the clinical efficacy of tacrolimus in the treatment of nephrotic syndrome

Author:

Li Min,Xu Min,Liu Wei,Gao Xin

Funder

Natural Science Foundation of Shandong Province

health technology development program in Shandong province

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference22 articles.

1. Lavjay Butani, Rajendra Ramsamooj. Experience with tacrolimus in children with steroid-resistant nephrotic syndrome[J]. Pediatr Nephrol 2009 Aug; 24(8): 1517–1523.

2. Ayako Wakamatsu, Yoshiyasu Fukusumi, Eriko Hasegawa, Masayuki Tomita, Toru Watanabe, Ichiei Narita, Hiroshi Kawachi. Role of calcineurin (CN) in kidney glomerular podocyte: CN inhibitor ameliorated proteinuria by inhibiting the redistribution of CN at the slit diaphragm [J]. Physiol Rep 2016 Mar; 4(6): e12679.

3. Chen Kai. Effects of CYP3A4/5 and MDR1 gene polymorphisms on tacrolimus and liver and kidney function in early stage after liver transplantation [D]. Luzhou Medical College, 2013.

4. Guidelines for the detection of drug metabolizing enzymes and drug target genes (Trial) overview. J Practical organ transplantation. 2015;05:257–67.

5. Wei Wei Xie. Study on the correlation between ABCB1 gene polymorphism and depression and antidepressant efficacy [D]. In: Central South University; 2013.

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