Author:
Grunsfeld Alexander A,Login Ivan S
Abstract
Abstract
Background
It is common knowledge that the frontal lobes mediate complex human behavior and that damage to these regions can cause executive dysfunction, apathy, disinhibition and personality changes. However, it is less well known that subcortical structures such as the caudate and thalamus are part of functionally segregated fronto-subcortical circuits, that can also alter behavior after injury.
Case presentation
We present a 57 year old woman who suffered penetrating brain injury during endoscopic sinus surgery causing right basal ganglia injury which resulted in an abulic syndrome.
Conclusion
Abulia does not result solely from cortical injury but can occur after disruption anywhere in the anterior cingulate circuit – in the case of our patient, most prominently at the right caudate.
Publisher
Springer Science and Business Media LLC
Subject
Clinical Neurology,General Medicine
Reference11 articles.
1. May M, Levine HL, Mester SJ, Schaitkin B: Complications of endoscopic sinus surgery: Analysis of 2108 patients – Incidence and prevention. Layngoscope. 1994, 104: 1080-1083.
2. Bhatia KP, Marsden CD: The behavioral and motor consequences of focal lesions of the basal ganglia in man. Brain. 1994, 117 (4): 859-876.
3. Caplan LR, Schmahmann JD, Kase CS, Feldmann E, Baquis G, Greenberg JP, Gorelick PB, Helgason C, Hier DB: Caudate infarcts. Arch Neurol. 1990, 47: 133-143.
4. Kumral E, Evyapan D, Balkir K: Acute caudate vascular lesions. Stroke. 1999, 30 (1): 100-108.
5. Etsuro M: Impact of subcortical ischemic lesions on behavior and cognition. Annals NYAS Online. 2002, 977: 403-410.
Cited by
17 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献