Author:
Hajishizari Sara,Imani Hossein,Mehranfar Sanaz,Saeed Yekaninejad Mir,Mirzababaei Atieh,Clark Cain C. T.,Mirzaei Khadijeh
Abstract
Abstract
Objective
Low resting metabolic rate (RMR), as a risk factor for weight gain and obesity, can be influenced by many factors. Empirical research has confirmed the role of appetite and related hormones in obesity and energy intake. This study aimed to investigate the relationship between appetite and related hormones in overweight or obese Iranian women with normal and hypo RMR.
Methods
This case–control study was conducted on 42 Iranian adult women (21 cases, and 21 controls), aged 18–48 years. An impedance body analyzer was used to obtain the body composition and an indirect calorimeter was used to assess the RMR. The Flint questionnaire was used to assess appetite, dietary intake, and physical activity were assessed by FFQ and IPAQ questionnaires respectively, and ELISA kits were used to assess leptin, ghrelin, and insulin hormones.
Results
The results of the study demonstrated a negative association between ghrelin hormone level (β = -0.34, 95%CI = -61.70,-3.86, P-value = 0.027) and RMR, and a positive association between insulin hormone level (β = 0.48, 95%CI = 9.38–34.35, P-value = 0.001) and RMR. Also, results of the appetite questionnaire showed that, in general, both appetite (β = 0.32, 95%CI = -0.10–2.99 P-value = 0.044) and hunger variable (β = 0.30, 95%CI = 0.04–5.87, P-value = 0.047) have a positive association with RMR. There was no significant association between leptin levels and RMR.
Conclusion
It is evident that appetite and related hormones have a potential role in promoting a normal RMR.
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health,Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)
Reference82 articles.
1. Taheri F, Kazemi T, Chahkandi T, Namakin K, ZARDAST M, Bijari B. Prevalence of overweight, obesity and central obesity among elementary school children in Birjand, east of Iran, 2012. 2013.
2. Morton G, Cummings D, Baskin D, Barsh G, Schwartz M. Central nervous system control of food intake and body weight. Nature. 2006;443(7109):289–95.
3. Pinheiro Volp A, de Oliveira F, Duarte Moreira Alves R, Esteves E, Bressan J. Energy expenditure: components and evaluation methods. Nutricion hospitalaria. 2011;26(3).
4. Svendsen OL, Hassager C, Christiansen C. Impact of regional and total body composition and hormones on resting energy expenditure in overweight postmenopausal women. Metabolism. 1993;42(12):1588–91.
5. Bouchard C, Tremblay A, Nadeau A, Despres J, Theriault G, Boulay M, et al. Genetic effect in resting and exercise metabolic rates. Metabolism. 1989;38(4):364–70.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献