Author:
Zheng Hai-Tao,Xu Yan,Yan Xiao-Yu,Yan Yong-Bin,Ma Shu-Xia,Liu Ling-Ling,Zhao Qian-Yi
Abstract
Abstract
Background
The hypereosinophilic syndrome (HES) is a group of rare blood disorders characterized by persistent eosinophilia and damage to multiple organs. HES can be either primary, secondary or idiopathic. Secondary HES are commonly caused by parasitic infections, allergic reactions or cancer. We described a pediatric case of HES associated with liver damage and multiple thrombi.
Case summary
A 12-year-old boy with eosinophilia was complicated with severe thrombocytopenia, liver damage, portal vein, splenic vein, and superior mesenteric vein thromboses. The thrombi recanalized after treatment with methylprednisolone succinate and low molecular weight heparin. No side effects appeared after 1-month.
Conclusions
Corticosteroids should be used at an early stage of HES to prevent further damage to vital organs. Anticoagulants should be recommended only in cases with thrombosis which should be actively screened as a part of evaluation of end organ damage.
Funder
Henan Province Chinese Medicine Special Research Project
Publisher
Springer Science and Business Media LLC
Subject
Pediatrics, Perinatology and Child Health