Resveratrol reduces store-operated Ca2+ entry and enhances the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats model via targeting ORAI1

Resveratrol reduces store-operated Ca2+ entry and enhances the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats model via targeting ORAI1–STIM1 complex

Published:2019-08-19 Issue:1 Volume:52 Page:
ISSN:0717-6287
Container-title:Biological Research
language:en
Short-container-title:Biol Res

Author:

Lu Jinsen,Yang Jiazhao,Zheng Yongshun,Fang Shiyuan,Chen Xiaoyu

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Link

http://link.springer.com/content/pdf/10.1186/s40659-019-0250-7.pdf

Reference34 articles.

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3. Zhang J, Song X, Cao W, Lu J, Wang X, Wang G, Wang Z, Chen X. Autophagy and mitochondrial dysfunction in adjuvant-arthritis rats treatment with resveratrol. Sci Rep. 2016;6:32928.

4. Tsai MH, Hsu LF, Lee CW, Chiang YC, Lee MH, How JM, Wu CM, Huang CL, Lee IT. Resveratrol inhibits urban particulate matter-induced COX-2/PGE2 release in human fibroblast-like synoviocytes via the inhibition of activation of NADPH oxidase/ROS/NF-kappaB. Int J Biochem Cell Biol. 2017;88:113–23.

5. Cao W, Zhang J, Wang G, Lu J, Wang T, Chen X. Reducing-autophagy derived mitochondrial dysfunction during resveratrol promotes fibroblast-like synovial cell apoptosis. Anat Rec. 2018;301:1179–88.

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