High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014

Author:

Dutcher Janice P,Schwartzentruber Douglas J,Kaufman Howard L,Agarwala Sanjiv S,Tarhini Ahmad A,Lowder James N,Atkins Michael B

Publisher

BMJ

Subject

Cancer Research,Pharmacology,Oncology,Molecular Medicine,Immunology,Immunology and Allergy

Reference59 articles.

1. Yang JC, Sherry RM, Steinberg SM, Topalian SL, Schwartzentruber DJ, Hwu P, Seipp CA, Rogers-Freezer L, Morton KE, White DE, Liewehr DJ, Merino MJ, Rosenberg SA: Randomized study of high-dose and low-dose Interleukin-2 in patients with metastatic renal cell cancer. J Clin Oncol. 2003, 21: 3127-3132. 10.1200/JCO.2003.02.122.

2. McDermott DF, Regan MM, Clark JI, Flaherty LE, Weiss GR, Logan TF, Kirkwood JM, Gordon MS, Sosman JA, Ernstoff MS, Tretter CPG, Urba WJ, Smith JW, Margolin KA, Mier JW, Gollob JA, Dutcher JP, Atkins MB: Randomized phase III trial of high dose Interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma. J Clin Oncol. 2005, 23: 133-141. 10.1200/JCO.2005.03.206.

3. Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Wiess G, Margolin K, Abrams J, Sznol M, Parkinson D, Hawkins M, Paradise C, Kunkel L, Rosenberg SA: High dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol. 1999, 17: 2105-2116.

4. Atkins MB, Kunkel L, Sznol M, Rosenberg SA: High dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am. 2000, 6 (Suppl 1): S11-S14.

5. Margolin KA, Rayner AA, Hawkins MJ, Atkins MB, Dutcher JP, Fisher RI, Weiss GR, Doroshow JH, Jaffe HS, Roper M: Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines. J Clin Oncol. 1989, 7: 486-498.

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