A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer-Reference-Cited by-同舟云学术

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A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer

Published:2019-11-15 Issue:1 Volume:7 Page:
ISSN:2051-1426
Container-title:Journal for ImmunoTherapy of Cancer
language:en
Short-container-title:j. immunotherapy cancer

Author:

Rammensee Hans-Georg,Wiesmüller Karl-Heinz,Chandran P. Anoop,Zelba Henning,Rusch Elisa,Gouttefangeas Cécile,Kowalewski Daniel J.,Di Marco Moreno,Haen Sebastian P.,Walz Juliane S.,Gloria Yamel Cardona,Bödder Johanna,Schertel Jill-Marie,Tunger Antje,Müller Luise,Kießler Maximilian,Wehner Rebekka,Schmitz Marc,Jakobi Meike,Schneiderhan-Marra Nicole,Klein Reinhild,Laske Karoline,Artzner Kerstin,Backert Linus,Schuster Heiko,Schwenck Johannes,Weber Alexander N. R.,Pichler Bernd J.,Kneilling Manfred,la Fougère Christian,Forchhammer Stephan,Metzler Gisela,Bauer Jürgen,Weide Benjamin,Schippert Wilfried,Stevanović Stefan,Löffler Markus W.^ORCID

Funder

FP7 Ideas: European Research Council

Ernst Jung Preis

Faculty of Medicine Carl Gustav Carus of the Technische Universität Dresden

Deutsche Forschungsgemeinschaft

Federal State Baden-Württemberg

Publisher

BMJ

Subject

Cancer Research,Pharmacology,Oncology,Molecular Medicine,Immunology,Immunology and Allergy

Link

http://link.springer.com/content/pdf/10.1186/s40425-019-0796-5.pdf

Reference50 articles.

1. Gubin MM, Zhang X, Schuster H, et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature. 2014;515(7528):577–81.

2. Luksza M, Riaz N, Makarov V, et al. A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy. Nature. 2017;551(7681):517–20.

3. Panda A, Betigeri A, Subramanian K, et al. Identifying a clinically applicable mutational burden threshold as a potential biomarker of response to immune checkpoint therapy in solid tumors. JCO Precis Oncol. 2017;2017.

4. Rini BI, Stenzl A, Zdrojowy R, et al. IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial. Lancet Oncol. 2016;17(11):1599–611.

5. Walter S, Weinschenk T, Stenzl A, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med. 2012;18(8):1254–61.

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