A calibrated agent-based computer model of stochastic cell dynamics in normal human colon crypts useful for in silico experiments

Author:

Bravo Rafael,Axelrod David E

Publisher

Springer Science and Business Media LLC

Subject

Health Informatics,Modelling and Simulation

Reference102 articles.

1. Binder HJ: Intestinal fluid and electrolyte movement. Medical physiology: a cellular and molecular approach boron. Edited by: Boron WF, Boulaep EL. 2012, Philadelphia: Saunders Elsevier, 933-948. 2

2. Li L, Clevers H: Coexistence of quiescent and active adult stem cells in mammals. Science. 2010, 327: 542-545. 10.1126/science.1180794.

3. Humphries A, Wright NA: Colonic crypt organization and tumorigenesis. Nature Rev Cancer. 2008, 8: 415-424. 10.1038/nrc2392.

4. Clevers H: The intestinal crypt, a prototype stem cell compartment. Cell. 2013, 154: 274-284. 10.1016/j.cell.2013.07.004.

5. Boman BM, Fields JZ, Bonham-Carter O, Runquist OA: Computer modeling implicates stem cell overproduction in colon cancer initiation. Cancer Res. 2001, 61: 8408-8411.

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