Dendrobium nobile Lindley and its bibenzyl component moscatilin are able to protect retinal cells from ischemia/hypoxia by dowregulating placental growth factor and upregulating Norrie disease protein
Author:
Publisher
Springer Science and Business Media LLC
Subject
Complementary and alternative medicine,General Medicine
Link
http://link.springer.com/content/pdf/10.1186/s12906-018-2256-z.pdf
Reference33 articles.
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2. Nikopoulos K, Venselaar H, Collin RW, Riveiro-Alvarez R, Boonstra FN, Hooymans JM, et al. Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP. Hum Mutat. 2010;31(6):656–66. https://doi.org/10.1002/humu.21250 .
3. Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, et al. Haploinsufficiency of RCBTB1 is associated with coats disease and familial exudative vitreoretinopathy. Hum Mol Genet. 2016;25(8):1637–47. https://doi.org/10.1093/hmg/ddw041 .
4. Wang Y, Rattner A, Zhou Y, Williams J, Smallwood PM, Nathans J. Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity. Cell. 2012;151:1332–44. https://doi.org/10.1016/j.cell.2012.10.042 .
5. Luhmann UFO, Lin J, Acar N, Lammel S, Feil S, Grimm C, et al. Role of the Norrie disease pseudoglioma gene in sprouting angiogenesis during development of the retinal vasculature. Invest Ophthalmol Vis Sci. 2005;46:3372–82. https://doi.org/10.1167/iovs.05-0174 .
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