Oxymatrine inhibits aldosterone-induced rat cardiac fibroblast proliferation and differentiation by attenuating smad-2,-3 and-4 expression: an in vitro study

Author:

Fu Lingyun,Xu Yini,Tu Ling,Huang Haifeng,Zhang Yanyan,Chen Yan,Tao Ling,Shen Xiangchun

Funder

National Natural Science Foundation of China

the Key Project for Science and Technology Foundation of Guizhou Province

Innovated Team of the Education Department of Guizhou Province

Scientific and Technologic Innovated Team of Guizhou Province

Program for New Century Excellent Talents in University (CN)

High level Innovation Talents

the 2011 Modern Drug of Cooperation Innovation

the scientific and technologic cooperation project of Guizhou province and Guiyang medical University

Publisher

Springer Science and Business Media LLC

Subject

Complementary and alternative medicine,General Medicine

Reference28 articles.

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2. Ebert AD, Diecke S, Chen IY, Wu JC. Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand. EMBO Mol Med. 2015;7:1–14.

3. Cannon MV, Silljé HHW, Sijbesma JWA, Baudoin IV, Ciapaite J, Sluis BVD, et al. Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization. EMBO Mol Med. 2015;5:1–15.

4. Doltra A, Messroghli D, Stawowy P, Hassel JH, Gebker R, Leppanen O, et al. Potential Reduction of Interstitial Myocardial Fibrosis With Renal Denervation. J Am Heart Assoc. 2014;3:1–10.

5. Meng GL, Zhu JB, Xiao YJ, Huang ZR, Zhang YQ, Tang X, et al. Hydrogen Sulfide Donor GYY4137 Protects against Myocardial Fibrosis. Oxidative Medicine Cellular Longevity. 2015;15:1–10.

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